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SGK1 Polyclonal Antibody, 100μg, (ATB-T4269)

$199.00
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Product Details

Background: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]Product datasheet: Overview Product Description SGK1 Polyclonal Antibody, 100μg, (ATB-T4269) Image Species Reactivities Human Immunogen Synthesized peptide derived from human SGK1 around the non-phosphorylation site of T256. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: A gene-based analysis of variants in the serum/glucocorticoid regulated kinase (SGK) genes with blood pressure responses to sodium intake: the GenSalt Study. Li C, et al. PLoS One, 2014. PMID 24878720 Free PMC Article Revealing the role of SGK1 in the dynamics of medulloblastoma using a mathematical model. Kawka J, et al. J Theor Biol, 2014 Aug 7. PMID 24685888 Urinary serum- and glucocorticoid-inducible kinase SGK1 reflects renal injury in patients with immunoglobulin A nephropathy. Lu X, et al. Nephrology (Carlton), 2014 Jun. PMID 24602173 Serum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death. Brickley DR, et al. J Biol Chem, 2013 Nov 8. PMID 24043625 Free PMC Article Serum and glucocorticoid inducible kinase, metabolic syndrome, inflammation, and tumor growth. Lang F, et al. Hormones (Athens), 2013 Apr-Jun. PMID 23933686

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SGK1 Polyclonal Antibody, 100μg, (ATB-T4269)
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