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SIP1 Polyclonal Antibody, 100μg, (ATB-T4300)

$199.00
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Product Details

Background: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]Product datasheet: Overview Product Description SIP1 Polyclonal Antibody, 100μg, (ATB-T4300) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the N-terminal region of human SIP1. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The single nucleotide polymorphisms in Smad-interacting protein 1 gene contribute to its ectopic expression and susceptibility in Hirschsprung's disease. Zhang S, et al. Exp Mol Pathol, 2014 Apr. PMID 24576558 ZEB2, a new candidate gene for asplenia. Pons L, et al. Orphanet J Rare Dis, 2014 Jan 8. PMID 24401652 Free PMC Article ZEB2-Sp1 cooperation induces invasion by upregulating cadherin-11 and integrin α5 expression. Nam EH, et al. Carcinogenesis, 2014 Feb. PMID 24130169 Protein expression of ZEB2 in renal cell carcinoma and its prognostic significance in patient survival. Fang Y, et al. PLoS One, 2013. PMID 23658743 Free PMC Article Expression of the ZEB2 gene in pancreatic stromal cells in pancreatic ductal adenocarcinoma, pancreatitis, and normal state. Usova EV, et al. Dokl Biol Sci, 2013 Jan. PMID 23479023

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SIP1 Polyclonal Antibody, 100μg, (ATB-T4300)
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