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SMUG1 Polyclonal Antibody, 100μg, (ATB-T4348)

$199.00
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Background: This gene encodes a protein that participates in base excision repair by removing uracil from single- and double-stranded DNA. Many alternatively spliced transcript variants exist for this gene; the full-length nature is known for some but not all of the variants. [provided by RefSeq, Aug 2011]Product datasheet: Overview Product Description SMUG1 Polyclonal Antibody, 100μg, (ATB-T4348) Image Species Reactivities Human,Mouse,Rat,Monkey Immunogen Synthesized peptide derived from the Internal region of human SMUG1. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy. Abdel-Fatah TM, et al. Breast Cancer Res Treat, 2013 Dec. PMID 24253812 Genetic variations in base excision repair pathway and risk of bladder cancer: a case-control study in the United States. Xie H, et al. Mol Carcinog, 2015 Jan. PMID 24038406 Single nucleotide polymorphisms in uracil-processing genes, intake of one-carbon nutrients and breast cancer risk. Marian C, et al. Eur J Clin Nutr, 2011 Jun. PMID 21427733 Free PMC Article Opposite-base dependent excision of 5-formyluracil from DNA by hSMUG1. Knaevelsrud I, et al. Int J Radiat Biol, 2009 May. PMID 19365746 Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase. Darwanto A, et al. J Biol Chem, 2009 Jun 5. PMID 19324873 Free PMC Article

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SMUG1 Polyclonal Antibody, 100μg, (ATB-T4348)
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