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SR-3D Polyclonal Antibody, 100μg, (ATB-T4402)

$199.00
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Background: The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]Product datasheet: Overview Product Description SR-3D Polyclonal Antibody, 100μg, (ATB-T4402) Image Species Reactivities Human Immunogen Synthesized peptide derived from the N-terminal region of human SR-3D. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E. Kapeller J, et al. J Comp Neurol, 2011 Feb 15. PMID 21192076 Free PMC Article Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E. Niesler B, et al. Gene, 2003 May 22. PMID 12801637 ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma. Nongpiur ME, et al. PLoS Genet, 2014 Mar. PMID 24603532 Free PMC Article Polymorphism in HTR3D shows different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy. Hammer C, et al. Pharmacogenomics, 2010 Jul. PMID 20602613 A cluster of novel serotonin receptor 3-like genes on human chromosome 3. Karnovsky AM, et al. Gene, 2003 Nov 13. PMID 14597179

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SR-3D Polyclonal Antibody, 100μg, (ATB-T4402)
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