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SR-4 Polyclonal Antibody, 100μg, (ATB-T4404)

$199.00
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Product Details

Background: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]Product datasheet: Overview Product Description SR-4 Polyclonal Antibody, 100μg, (ATB-T4404) Image Species Reactivities Human,Rat Immunogen Synthesized peptide derived from the Internal region of human SR-4. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: HTR4 gene structure and altered expression in the developing lung. Hodge E, et al. Respir Res, 2013 Jul 26. PMID 23890215 Free PMC Article Human 5-HT₄receptor stimulation in atria of transgenic mice. Gergs U, et al. Naunyn Schmiedebergs Arch Pharmacol, 2013 May. PMID 23307014 Association and CpG SNP analysis of HTR4 polymorphisms with suicidal behavior in subjects with schizophrenia. Polsinelli G, et al. J Neural Transm, 2013 Feb. PMID 22842674 Obesity is associated with high serotonin 4 receptor availability in the brain reward circuitry. Haahr ME, et al. Neuroimage, 2012 Jul 16. PMID 22709820 Association of 5-hydroxytryptamine (serotonin) receptor 4 (5-HTR4) gene polymorphisms with asthma. Kim TH, et al. Respirology, 2011 May. PMID 21382128

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SR-4 Polyclonal Antibody, 100μg, (ATB-T4404)
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