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SSTR1 Polyclonal Antibody, 100μg, (ATB-T4429)

$199.00
In stock
Product Details

Background: Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012]Product datasheet: Overview Product Description SSTR1 Polyclonal Antibody, 100μg, (ATB-T4429) Image Species Reactivities Human,Mouse,Rat,Monkey Immunogen Synthesized peptide derived from the N-terminal region of human SSTR1. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Somatostatin receptor expression in Merkel cell carcinoma as target for molecular imaging. Buder K, et al. BMC Cancer, 2014 Apr 17. PMID 24742330 Free PMC Article Does somatostatin have a role in the regulation of cortisol secretion in primary pigmented nodular adrenocortical disease (ppnad)? a clinical and in vitro investigation. Bram Z, et al. J Clin Endocrinol Metab, 2014 May. PMID 24512486 Somatostatin receptor-based molecular imaging and therapy for neuroendocrine tumors. Wang L, et al. Biomed Res Int, 2013. PMID 24106690 Free PMC Article Somatostatin receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer. Zhao J, et al. Br J Cancer, 2013 Jun 25. PMID 23722468 Free PMC Article Somatostatin receptor-1 induces cell cycle arrest and inhibits tumor growth in pancreatic cancer. Li M, et al. Cancer Sci, 2008 Nov. PMID 18823376 Free PMC Article

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SSTR1 Polyclonal Antibody, 100μg, (ATB-T4429)
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