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T2R43 Polyclonal Antibody, 100μg, (ATB-T4510)

$199.00
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Product Details

Background: TAS2R43 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.[supplied by OMIM, Mar 2009]Product datasheet: Overview Product Description T2R43 Polyclonal Antibody, 100μg, (ATB-T4510) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human T2R43. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN). Wooding SP, et al. BMC Med Genet, 2012 Oct 11. PMID 23050764 Free PMC Article Extraoral bitter taste receptors as mediators of off-target drug effects. Clark AA, et al. FASEB J, 2012 Dec. PMID 22964302 Free PMC Article Motile cilia of human airway epithelia are chemosensory. Shah AS, et al. Science, 2009 Aug 28. PMID 19628819 Free PMC Article Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin. Pronin AN, et al. Curr Biol, 2007 Aug 21. PMID 17702579 Bitter taste receptors for saccharin and acesulfame K. Kuhn C, et al. J Neurosci, 2004 Nov 10. PMID 15537898

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T2R43 Polyclonal Antibody, 100μg, (ATB-T4510)
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