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TBX3 Polyclonal Antibody, 100μg, (ATB-T4571)
Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description TBX3 Polyclonal Antibody, 100μg, (ATB-T4571) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human TBX3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Genetic and functional analysis of the TBX3 gene promoter in indirect inguinal hernia. Zhao Z, et al. Gene, 2015 Jan 1. PMID 25455105 TBX3, a downstream target of TGF-β1, inhibits mesangial cell apoptosis. Wensing LA, et al. Exp Cell Res, 2014 Nov 1. PMID 25158279 TBX3 regulates splicing in vivo: a novel molecular mechanism for Ulnar-mammary syndrome. Kumar P P, et al. PLoS Genet, 2014 Mar. PMID 24675841 Free PMC Article The T-box transcription factor, TBX3, is sufficient to promote melanoma formation and invasion. Peres J, et al. Mol Cancer, 2013 Oct 7. PMID 24098938 Free PMC Article Mutations in exon 2 of TBX3 are rare in common human tumors. Yoo NJ, et al. APMIS, 2014 Feb. PMID 23656610
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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