TDAG51 Polyclonal Antibody, 100µg, (ATB-T4590)

Background: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.Product datasheet: Overview Product Description TDAG51 Polyclonal Antibody, 100µg, (ATB-T4590) Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human TDAG51. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year Clonality Polyclonal References: Assignment of the human PHLDA1 gene to chromosome 12q15 by radiation hybrid mapping. Kuske M.D., Johnson J.P.Cytogenet. Cell Genet. 89:1-1(2000) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. A cDNA, which predicts a protein with PQ-rich repeats, isolated from a phage library of human fetal liver tissue. Wagner F.F., Flegel W.A.Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Fetal liver. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 53-401. Tissue: Brain and Uterus. Identification of the human PHLDA1/TDAG51 gene: down-regulation in metastatic melanoma contributes to apoptosis resistance and growth deregulation. Neef R., Kuske M.A., Proels E., Johnson J.P.Cancer Res. 62:5920-5929(2002) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 350-401, TISSUE SPECIFICITY. Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product. Hinz T., Flindt S., Marx A., Janssen O., Kabelitz D.Cell. Signal. 13:345-352(2001) [PubMed] [Europe PMC] Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH RPL14; EIF3S7 AND PABPC4. TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia. Hossain G.S., van Thienen J.V., Werstuck G.H., Zhou J., Sood S.K., Dickhout J.G., de Koning A.B., Tang D., Wu D., Falk E., Poddar R., Jacobsen D.W., Zhang K., Kaufman R.J., Austin R.C.J. Biol. Chem. 278:30317-30327(2003) [PubMed] [Europe PMC] Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION. N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].