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TIP60 Polyclonal Antibody, 100μg, (ATB-T4666)

$199.00
In stock
Product Details

Background: The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description TIP60 Polyclonal Antibody, 100μg, (ATB-T4666) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human TIP60 around the non-phosphorylation site of S90. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: RVBs are required for assembling a functional TIP60 complex. Jha S, et al. Mol Cell Biol, 2013 Mar. PMID 23297341 Free PMC Article Tip60 degradation by adenovirus relieves transcriptional repression of viral transcriptional activator EIA. Gupta A, et al. Oncogene, 2013 Oct 17. PMID 23178490 Free PMC Article Role of Tip60 in human melanoma cell migration, metastasis, and patient survival. Chen G, et al. J Invest Dermatol, 2012 Nov. PMID 22673729 TIP60 as a potential marker for the malignancy of gastric cancer. Sakuraba K, et al. Anticancer Res, 2011 Jan. PMID 21273583 Involvement of TIP60 acetyltransferase in intracellular Salmonella replication. Wang X, et al. BMC Microbiol, 2010 Aug 26. PMID 20796290 Free PMC Article

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TIP60 Polyclonal Antibody, 100μg, (ATB-T4666)
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