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TPH2 Polyclonal Antibody, 100μg, (ATB-T4711)
Background: This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description TPH2 Polyclonal Antibody, 100μg, (ATB-T4711) Image Species Reactivities Human,Mouse,Rat,Monkey Immunogen Synthesized peptide derived from human TPH2 around the non-phosphorylation site of S19. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Functional characterization of the S41Y (C2755A) polymorphism of tryptophan hydroxylase 2. Carkaci-Salli N, et al. J Neurochem, 2014 Sep. PMID 24899127 TPH2 gene polymorphisms in the regulatory region are associated with paranoid schizophrenia in Northern Han Chinese. Xu XM, et al. Genet Mol Res, 2014 Mar 12. PMID 24668623 Tryptophan hydroxylase 2 gene polymorphisms in Japanese patients with medication overuse headaches. Ishii M, et al. Acta Neurol Taiwan, 2013 Dec. PMID 24458851 Regulatory variant of the TPH2 gene and early life stress are associated with heightened attention to social signals of fear in infants. Forssman L, et al. J Child Psychol Psychiatry, 2014 Jul. PMID 24304270 Stimulation of 5-HT2C receptors improves cognitive deficits induced by human tryptophan hydroxylase 2 loss of function mutation. Del'Guidice T, et al. Neuropsychopharmacology, 2014 Apr. PMID 24196946
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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