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TULA Polyclonal Antibody, 100μg, (ATB-T4782)

$199.00
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Product Details

Background: This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]Product datasheet: Overview Product Description TULA Polyclonal Antibody, 100μg, (ATB-T4782) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human TULA. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Evidence of new risk genetic factor to systemic lupus erythematosus: the UBASH3A gene. Diaz-Gallo LM, et al. PLoS One, 2013. PMID 23565265 Free PMC Article rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk HLA-DR,DQ genotypes. Johnson K, et al. Pediatr Diabetes, 2012 Dec. PMID 22776074 TULA-family proteins: an odd couple. Tsygankov AY. Cell Mol Life Sci, 2009 Sep. PMID 19585081 Multidomain STS/TULA proteins are novel cellular regulators. Tsygankov AY. IUBMB Life, 2008 Apr. PMID 18344182 Isolation and characterization of the UBASH3A gene on 21q22.3 encoding a potential nuclear protein with a novel combination of domains. Wattenhofer M, et al. Hum Genet, 2001 Feb. PMID 11281453

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TULA Polyclonal Antibody, 100μg, (ATB-T4782)
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