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Tuberin Polyclonal Antibody, 100μg, (ATB-T4776)
Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Tuberin Polyclonal Antibody, 100μg, (ATB-T4776) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human Tuberin around the non-phosphorylation site of S981. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The analysis of mutations and exon deletions at TSC2 gene in angiomyolipomas associated with tuberous sclerosis complex. Yang HM, et al. Exp Mol Pathol, 2014 Dec. PMID 25281918 Severity of manifestations in tuberous sclerosis complex in relation to genotype. Kothare SV, et al. Epilepsia, 2014 Jul. PMID 24917535 Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2. Demetriades C, et al. Cell, 2014 Feb 13. PMID 24529380 Free PMC Article A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation. Munkley J, et al. Oncotarget, 2014 Jan 15. PMID 24318044 Free PMC Article Sun exposure causes somatic second-hit mutations and angiofibroma development in tuberous sclerosis complex. Tyburczy ME, et al. Hum Mol Genet, 2014 Apr 15. PMID 24271014
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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What products do you offer?
At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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We ship our medical lab equipment to customers nationwide. Browse our online shop to view our impressive inventory of available lab equipment today and purchase the products that meet your unique style and needs. We can't wait to prove why Intelixbio.com is one of the nation's best medical lab supply providers.
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When you contact our team, you can expect fast, friendly, and professional assistance with all your medical lab equipment needs.