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UBF Polyclonal Antibody, 100μg, (ATB-T4803)

$199.00
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Product Details

Background: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]Product datasheet: Overview Product Description UBF Polyclonal Antibody, 100μg, (ATB-T4803) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human UBF around the non-phosphorylation site of S484. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Involvement of phosphatidylinositol 4,5-bisphosphate in RNA polymerase I transcription. Yildirim S, et al. J Cell Sci, 2013 Jun 15. PMID 23591814 [Expression profiling of UBF, a novel member of UBC family]. Cui CP, et al. Zhongguo Ying Yong Sheng Li Xue Za Zhi, 2004 Feb. PMID 21162312 Temperature-induced partially unfolded state of hUBF HMG Box-5: conformational and dynamic investigations of the Box-5 thermal intermediate ensemble. Liu Z, et al. Proteins, 2009 Nov 1. PMID 19452555 Nucleolar localization of upstream binding factor in HeLa cells depends on rRNA synthesis activities. He J, et al. Folia Biol (Praha), 2008. PMID 19393134 Upstream-binding factor is sequestered into herpes simplex virus type 1 replication compartments. Stow ND, et al. J Gen Virol, 2009 Jan. PMID 19088274 Free PMC Article

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UBF Polyclonal Antibody, 100μg, (ATB-T4803)
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