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USP48 Polyclonal Antibody, 100μg, (ATB-T4843)

$199.00
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Background: This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description USP48 Polyclonal Antibody, 100μg, (ATB-T4843) Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human USP48. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Identification of the human ubiquitin specific protease 31 (USP31) gene: structure, sequence and expression analysis. Lockhart PJ, et al. DNA Seq, 2004 Feb. PMID 15354349 Regulation of ubiquitin-dependent processes by deubiquitinating enzymes. Wilkinson KD. FASEB J, 1997 Dec. PMID 9409543 Dopamine D3 receptor inhibits the ubiquitin-specific peptidase 48 to promote NHE3 degradation. Armando I, et al. FASEB J, 2014 Mar. PMID 24308971 Free PMC Article Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-kappaB. Tzimas C, et al. Cell Signal, 2006 Jan. PMID 16214042 A strategy for modulation of enzymes in the ubiquitin system. Ernst A, et al. Science, 2013 Feb 1. PMID 23287719 Free PMC Article

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USP48 Polyclonal Antibody, 100μg, (ATB-T4843)
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