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VPAC2 Polyclonal Antibody, 100μg, (ATB-T4888)

$199.00
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Background: This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011]Product datasheet: Overview Product Description VPAC2 Polyclonal Antibody, 100μg, (ATB-T4888) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human VPAC2. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Monocytes from Sjögren's syndrome patients display increased vasoactive intestinal peptide receptor 2 expression and impaired apoptotic cell phagocytosis. Hauk V, et al. Clin Exp Immunol, 2014 Sep. PMID 24827637 A competitive PCR assay confirms the association of a copy number variation in the VIPR2 gene with schizophrenia in Han Chinese. Yuan J, et al. Schizophr Res, 2014 Jun. PMID 24794882 Genetic susceptibility to refractive error: association of vasoactive intestinal peptide receptor 2 (VIPR2) with high myopia in Chinese. Yiu WC, et al. PLoS One, 2013. PMID 23637909 Free PMC Article Low-copy repeats at the human VIPR2 gene predispose to recurrent and nonrecurrent rearrangements. Beri S, et al. Eur J Hum Genet, 2013 Jul. PMID 23073313 Free PMC Article Genome-wide investigation of rare structural variants identifies VIPR2 as a new candidate gene for schizophrenia. Nieratschker V, et al. Expert Rev Neurother, 2011 Jul. PMID 21721910

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VPAC2 Polyclonal Antibody, 100μg, (ATB-T4888)
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