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X11γ Polyclonal Antibody, 100μg, (ATB-T4911)

$199.00
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Product Details

Background: The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description X11γ Polyclonal Antibody, 100μg, (ATB-T4911) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human X11γ. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Amyloid precursor protein associates independently and collaboratively with PTB and PDZ domains of mint on vesicles and at cell membrane. Okamoto M, et al. Neuroscience, 2001. PMID 11440799 Genomic organization of the human X11L2 gene (APBA3), a third member of the X11 protein family interacting with Alzheimer's beta-amyloid precursor protein. Tanahashi H, et al. Neuroreport, 1999 Aug 20. PMID 10574372 Recruitment of the Mint3 adaptor is necessary for export of the amyloid precursor protein (APP) from the Golgi complex. Caster AH, et al. J Biol Chem, 2013 Oct 4. PMID 23965993 Free PMC Article Interaction of Mint3 with Furin regulates the localization of Furin in the trans-Golgi network. Han J, et al. J Cell Sci, 2008 Jul 1. PMID 18544638 Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network. Shrivastava-Ranjan P, et al. Mol Biol Cell, 2008 Jan. PMID 17959829 Free PMC Article

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X11γ Polyclonal Antibody, 100μg, (ATB-T4911)
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