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ZO-2 Polyclonal Antibody, 100μg, (ATB-T4993)
Background: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]Product datasheet: Overview Product Description ZO-2 Polyclonal Antibody, 100μg, (ATB-T4993) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human ZO-2 around the non-phosphorylation site of Y1118. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Mutations in TJP2 cause progressive cholestatic liver disease. Sambrotta M, et al. Nat Genet, 2014 Apr. PMID 24614073 Free PMC Article Alu-related transcript of TJP2 gene as a marker for colorectal cancer. Kim YJ, et al. Gene, 2013 Jul 25. PMID 23612256 ZO-2, a tight junction scaffold protein involved in the regulation of cell proliferation and apoptosis. Gonzalez-Mariscal L, et al. Ann N Y Acad Sci, 2012 Jun. PMID 22671599 Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctions. Fanning AS, et al. Ann N Y Acad Sci, 2009 May. PMID 19538295 Free PMC Article Structure of the second PDZ domain from human zonula occludens 2. Chen H, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2009 Apr 1. PMID 19342771 Free PMC Article
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Why is IntelixBio LLC so popular?
IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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What products do you offer?
At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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We ship our medical lab equipment to customers nationwide. Browse our online shop to view our impressive inventory of available lab equipment today and purchase the products that meet your unique style and needs. We can't wait to prove why Intelixbio.com is one of the nation's best medical lab supply providers.
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You can reach IntelixBio LLC by phone at 240-316-3161, by email at info@intelixbio.com, or by filling out one of the contact forms on our website.
When you contact our team, you can expect fast, friendly, and professional assistance with all your medical lab equipment needs.