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cGKII Polyclonal Antibody, 100μg, (ATB-T0891)

$199.00
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Background: This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]Product datasheet: Overview Product Description cGKII Polyclonal Antibody, 100μg, (ATB-T0891) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human cGKII around the non-phosphorylation site of S126. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Common variants of cGKII/PRKG2 are not associated with gout susceptibility. Sakiyama M, et al. J Rheumatol, 2014 Jul. PMID 24882840 Type II cGMP-dependent protein kinase inhibits ERK/JNK-mediated activation of transcription factors in gastric cancer cells. Sang J, et al. Mol Med Rep, 2012 Nov. PMID 22940826 Type II cGMP-dependent protein kinase inhibits EGF-induced MAPK/JNK signal transduction in breast cancer cells. Lan T, et al. Oncol Rep, 2012 Jun. PMID 22427012 Type II cGMP-dependent protein kinase inhibits EGF-triggered signal transduction of the MAPK/ERK-mediated pathway in gastric cancer cells. Wu Y, et al. Oncol Rep, 2012 Feb. PMID 22012247 Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Swartling FJ, et al. Oncogene, 2009 Sep 3. PMID 19543319 Free PMC Article

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cGKII Polyclonal Antibody, 100μg, (ATB-T0891)
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